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How does the metabolic pathway of a drug affect its efficacy and toxicity in the human body? Provide examples of drugs that undergo extensive metabolism and discuss how their metabolites contribute to their effects and side effects.
answered
Feb 20
in
Medicinal Chemistry
1
answer
36
views
What is the ideal reaction conditions, including temperature and catalyst choice, for the synthesis of polystyrene from styrene monomer to achieve the highest possible conversion and molecular weight of the polymer?
answered
Feb 20
in
Chemical synthesis
1
answer
27
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What is the effect of molecular shape on the phase behavior of a liquid crystal using Monte Carlo simulations?
answered
Feb 19
in
Computational Chemistry
1
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34
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What is the bond dissociation energy (in kJ/mol) of HBr molecule if it requires 364.4 kJ of energy to break one mole of HBr bonds?
asked
Feb 18
in
Chemical bonding
1
answer
40
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What are the key characteristics of the new methods for the synthesis of zeolites and how do they compare to traditional synthesis methods in terms of efficiency, cost-effectiveness, and practicality?
asked
Feb 13
in
Materials Chemistry
1
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36
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What is the role of metal ions in the structure and function of metalloenzymes and metalloproteins? Provide examples of metalloenzymes and metalloproteins, and explain how the metal ion(s) are involved in their catalytic activity.
asked
Feb 13
in
Coordination Chemistry
1
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52
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What is the molar mass of iron(III) sulfate hexahydrate?
answered
Feb 13
in
Inorganic Chemistry
1
answer
42
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How can we design drugs that specifically target and inhibit the growth of gram-negative bacteria, such as E. coli or P. aeruginosa, while leaving the beneficial gut microbiota unharmed?
asked
Feb 12
in
Medicinal Chemistry
1
answer
41
views
How can the properties of a polymer be modified to create a smart material that is sensitive to changes in temperature?
asked
Feb 10
in
Polymer Chemistry
1
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28
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How can the electronic properties of semiconductors be modified to optimize their performance as electronic devices, and what is the most effective method for achieving this modification?
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Feb 7
in
Materials Chemistry
1
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75
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What is the effect of changing the concentration of reaction intermediates on the rate of the chemical reaction?
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Feb 3
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Chemical kinetics
1
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112
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How does the concentration of copper ions in a given sample of water extracted from a polluted river affect the peak current observed in a cyclic voltammogram using a copper electrode?
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Jan 30
in
Analytical Chemistry
1
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83
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How did William James contribute to our understanding of consciousness?
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Jan 20
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Psychology
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50
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Where did the idea of mindfulness-based interventions originate?
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Jan 20
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Psychology
1
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69
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According to the cocktail party effect, how do people selectively attend to certain stimuli in a noisy environment?
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Jan 20
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Psychology
1
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49
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According to terror management theory, how does mortality salience influence gender?
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Jan 20
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Psychology
1
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50
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What was Stanley Milgram's obedience experiment?
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Jan 20
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Psychology
1
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136
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How did Francis Crick and Christof Koch's work inform us about the neural correlates of consciousness?
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Jan 17
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Psychology
1
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51
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What is a corpus in discursive psychology?
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Jan 16
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Psychology
1
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31
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Why is it necessary to consider the impact of cultural appropriation when evaluating eating disorders?
asked
Jan 16
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Psychology
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