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How can we design a drug that will specifically target and inhibit the activity of the enzyme dihydrofolate reductase, which is responsible for the synthesis of folate necessary for DNA replication in cancer cells, without affecting healthy cells?

asked Feb 12 in Medicinal Chemistry by KreogMoore5 (6.4k points)

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How can we design a novel antiviral drug that effectively targets viral replication while minimizing harmful side-effects in the human body?

asked Feb 12 in Medicinal Chemistry by AndrewSisley (2.1k points)

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How does the coordination chemistry of metalloproteins and enzymes contribute to their biological function and provide insights into their mechanisms of action?

asked Feb 12 in Coordination Chemistry by IsabelleTitu (1.8k points)

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What is the boiling point of copper (II) sulfate (CuSO4) at a pressure of 1 atmosphere?

asked Feb 12 in Inorganic Chemistry by CecileBills (2.2k points)

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How does the electronic structure of a crystal of gold differ from that of a crystal of silver, as determined using density functional theory calculations?

asked Feb 12 in Computational Chemistry by ClairWaite7 (1.8k points)

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What is the role of cholesterol in maintaining the fluidity and permeability of the cell membrane?

asked Feb 12 in BioChemistry by IsabellaOcto (1.9k points)

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How can we design a drug that specifically targets the serotonin receptor 5-HT1A in the brain and has minimal side effects on other receptors, to effectively treat depression?

asked Feb 12 in Medicinal Chemistry by WileyBaskerv (2.2k points)

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What is the difference in coordination chemistry between metallofullerenes and metalloclusters, and how does this impact their properties and potential applications in industries such as pharmaceuticals and electronics?

asked Feb 12 in Coordination Chemistry by TroyWitcher8 (2.1k points)

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How does the coordination chemistry of metalloproteins regulate enzymatic activity? Provide specific examples and discuss the role of metal ions in catalysis.

asked Feb 12 in Coordination Chemistry by RaulGalway75 (2.1k points)

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How does the coordination chemistry principles of chelation therapy help in removing toxic metals from the human body? Provide specific examples of chelating agents and their structure.

asked Feb 12 in Coordination Chemistry by LinCheatham (2.0k points)

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What is the chemical mechanism behind CFCs that lead to the destruction of ozone molecules?

asked Feb 12 in Environmental Chemistry by Marilynn3793 (2.1k points)

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How can we design drugs that target specific types of bacteria without harming beneficial bacteria in the body?

asked Feb 12 in Medicinal Chemistry by SvenJonathan (1.9k points)

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How can we design drugs that effectively target a specific type of bacteria without harming the beneficial bacteria in the body?

asked Feb 12 in Medicinal Chemistry by ClydeC545764 (2.2k points)

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How does the coordination chemistry of metalloenzymes and metalloproteins affect their functions in biological systems? Provide specific examples to support your answer.

asked Feb 12 in Coordination Chemistry by RudyMms5536 (1.8k points)

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How does the deficiency of the enzyme cystathionine beta-synthase (CBS) affect the metabolism of methionine and homocysteine in the body? And how can this condition lead to inherited diseases like homocystinuria in humans?

asked Feb 12 in BioChemistry by HolliePutman (2.0k points)

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How can we design drugs that specifically target the spike protein of the SARS-CoV-2 virus while avoiding interference with other cellular proteins?

asked Feb 12 in Medicinal Chemistry by Sung68J56969 (2.2k points)

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How does the coordination chemistry of metalloenzymes and metalloproteins affect their catalytic activity? Provide specific examples from recent research in the field.

asked Feb 12 in Coordination Chemistry by LouellaKinar (2.0k points)

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How can we design an efficient and cost-effective system for the recovery of valuable metals such as gold, silver, copper, and platinum from electronic waste?

asked Feb 12 in Chemical engineering by SelenaRonan (2.2k points)

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How can we design a drug that targets the root cause of genetic disorders, such as gene mutations, and effectively delivers the therapeutic agent to the target tissues and cells in the human body?

asked Feb 12 in Medicinal Chemistry by KaylaTibbett (1.9k points)

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Identify and explain the structural differences between cis-2-butene and trans-2-butene, and predict how these isomers would react differently in a chemical reaction with hydrogen gas.

asked Feb 12 in Organic Chemistry by AnaYdc643424 (1.8k points)

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