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How does the presence of chaperone proteins affect the folding of newly synthesized proteins?

asked Feb 12 in BioChemistry by BarbraBelang (2.1k points)

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How can we design a new drug for cancer treatment that targets specific cancer cells without affecting healthy cells, by utilizing the principles of medicinal chemistry?

asked Feb 12 in Medicinal Chemistry by Patsy0696347 (1.8k points)

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How can we use computational chemistry and molecular modeling to predict the behavior and interactions of a specific chemical compound under different environmental conditions, such as temperature and pressure?

asked Feb 12 in Physical Chemistry by BFFRachelle (1.8k points)

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What is the coordination geometry and oxidation state of the metal ion in the active site of cytochrome c oxidase, an important metalloenzyme involved in the respiratory process of living organisms?

asked Feb 12 in Coordination Chemistry by RosieBloom03 (1.8k points)

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How does cyclic AMP (cAMP) synthesis and breakdown regulate signal transduction pathways, and what is the role of adenylate cyclase and phosphodiesterase enzymes in this process?

asked Feb 12 in BioChemistry by SterlingIsr (1.7k points)

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How can the yield of a pharmaceutical drug production process be improved to increase the overall efficiency and reduce the cost of production?

asked Feb 13 in Chemical engineering by TomokoSorian (2.2k points)

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How does the coordination chemistry of metalloenzymes and metalloproteins affect their structure and function? Provide examples of metalloenzymes or metalloproteins and explain how their coordination chemistry contributes to their catalytic activity.

asked Feb 12 in Coordination Chemistry by HarryNewell7 (1.9k points)

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What is the synthesis process of the coordination compound cisplatin and how is its structure characterized using modern analytical techniques?

asked Feb 12 in Coordination Chemistry by JuanitaPiess (2.1k points)

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What is the predicted color of copper(II) sulfate pentahydrate ([Cu(H2O)4]SO4•H2O) based on its electronic configuration?

asked Feb 12 in Inorganic Chemistry by GeraldoPatte (1.7k points)

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How can we design a new metal-organic framework with increased water stability and enhanced gas adsorption properties for potential use in gas storage and industrial applications?

asked Feb 12 in Coordination Chemistry by EusebiaGilla (1.8k points)

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How can we control the molecular weight of a polymer synthesized through free radical polymerization?

asked Feb 12 in Organic Chemistry by LeoOverby677 (2.1k points)

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How does the crystal field theory explain the spectrochemical series of ligands and their corresponding colors in coordination compounds? Provide an example of a coordination compound and explain how its color can be predicted using crystal field theory.

asked Feb 12 in Coordination Chemistry by ClintCasiano (1.8k points)

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How does the coordination chemistry of chelating agents affect their ability to bind with metal ions for potential application in chelation therapy?

asked Feb 12 in Coordination Chemistry by CesarForlong (1.7k points)

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How can we explain the role of chemistry in everyday life to a non-science person? Provide three specific examples to illustrate your explanation.

asked Feb 12 in Chemical education by KariMcCleary (1.5k points)

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How can we design drugs that target specific viral proteins, inhibiting viral replication without harming host cells?

asked Feb 12 in Medicinal Chemistry by VictorinaWoz (1.9k points)

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How can we design a drug that specifically targets the dopamine receptor in the brain, and what chemical modifications can be made to increase its affinity and potency for this receptor?

asked Feb 12 in Medicinal Chemistry by ChristopherF (2.0k points)

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How do chaperone proteins facilitate the correct folding of newly synthesized proteins in the cell?

asked Feb 12 in BioChemistry by MarioGgq4193 (2.4k points)

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How can we design drugs that target specific genetic mutations implicated in diseases such as cystic fibrosis, sickle cell anemia, and Huntington's disease?

asked Feb 12 in Medicinal Chemistry by Hugo83583981 (1.5k points)

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How can we design drugs for the treatment of Alzheimer's disease that can effectively target and inhibit the activity of beta-amyloid protein aggregation in the brain?

asked Feb 12 in Medicinal Chemistry by ElisaWestgar (1.8k points)

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How can we design a drug that specifically targets gram-negative bacteria without harming the beneficial gram-positive bacteria present in the human gut microbiome?

asked Feb 12 in Medicinal Chemistry by AustinL82055 (1.8k points)

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