Recent questions in Medicinal Chemistry

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How does altering the chemical structures of a drug affect its pharmacodynamics and target interaction in the human body?

asked Jan 31 in Medicinal Chemistry by PercyEdmonds (1.8k points)

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1 answer 117 views

What are the mechanisms of action and potential therapeutic applications of natural products containing alkaloids for the treatment of chronic pain?

asked Jan 31 in Medicinal Chemistry by Lowell36338 (1.9k points)

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1 answer 143 views

How do acidic drugs interact with basic drugs and how can this interaction affect their therapeutic benefits and toxicities?

asked Jan 30 in Medicinal Chemistry by LizaSwenson (1.7k points)

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1 answer 153 views

How does the liver metabolize the drug acetylsalicylic acid (aspirin) and what are the potential metabolic pathways and metabolites formed in the process?

asked Jan 30 in Medicinal Chemistry by AgustinSteed (2.2k points)

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1 answer 135 views

How do the enzymes in the liver metabolize the commonly used painkiller acetaminophen and what are the consequences of the metabolites produced on the liver and other organs of the body?

asked Jan 30 in Medicinal Chemistry by ClaritaTrive (2.4k points)

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1 answer 134 views

How does the drug acetaminophen reduce fever and relieve pain in the human body at the molecular level?

asked Jan 30 in Medicinal Chemistry by IWHJaxon1452 (2.1k points)

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1 answer 137 views

How does the liver metabolize the drug acetaminophen, and what are the potential consequences of its metabolism by different cytochrome P450 enzymes in terms of drug efficacy and toxicity?

asked Jan 30 in Medicinal Chemistry by JamaalEnnor6 (1.9k points)

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1 answer 86 views

How does the drug acetaminophen work in the human body, and what types of biochemical reactions does it participate in?

asked Jan 30 in Medicinal Chemistry by ShadStansbur (1.8k points)

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1 answer 127 views

What drug delivery system can be optimized for the oral delivery of an anti-cancer drug to enhance its efficacy and minimize side effects? Specifically, what type of nanoparticle drug delivery system can be designed and synthesized to effectively deliver the drug to the target site while maintaining therapeutic efficacy and minimizing toxicity?

asked Jan 30 in Medicinal Chemistry by AstridMusser (1.9k points)

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1 answer 133 views

What novel drug delivery system could be designed for an anti-cancer drug that typically has low bioavailability and improved efficacy, using principles of medicinal chemistry and optimization techniques?

asked Jan 30 in Medicinal Chemistry by KaiRazo33412 (1.9k points)

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1 answer 70 views

How can a medicinal chemist utilize structure-based drug design to develop new treatments for respiratory diseases such as asthma, COPD, and cystic fibrosis?

asked Jan 30 in Medicinal Chemistry by KyleSchlemme (2.1k points)

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1 answer 162 views

How can a medicinal chemist develop a new treatment for cardiovascular diseases that targets the underlying causes of the disease, such as arterial stiffness and atherosclerosis, while also minimizing potential side effects on other physiological processes in the body?

asked Jan 30 in Medicinal Chemistry by LaunaRxf8120 (1.7k points)

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1 answer 130 views

How can a medicinal chemist design a drug to treat a specific genetic disorder, such as cystic fibrosis, by targeting the genetic mutation responsible for the disease?

asked Jan 30 in Medicinal Chemistry by BridgetteCul (2.3k points)

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1 answer 80 views

How can a medicinal chemist design a drug to selectively target the enzyme (or receptor) of interest and avoid non-specific interactions with other proteins in the body?

asked Jan 30 in Medicinal Chemistry by LaunaRxf8120 (1.7k points)

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1 answer 141 views

What is the effect of a drug that has low lipophilicity and high molecular weight on its absorption and distribution in the body? How do these properties impact the drug's pharmacokinetics?

asked Jan 30 in Medicinal Chemistry by Hugo83583981 (1.5k points)

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1 answer 157 views

How can a better understanding of an individual's genetic makeup aid in predicting their response to certain drugs and improve the efficacy of drug therapy?

asked Jan 30 in Medicinal Chemistry by TomokoSorian (2.2k points)

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1 answer 146 views

How does the CYP3A4 enzyme affect the metabolism and potential interactions of commonly prescribed drugs in the treatment of cardiovascular disease?

asked Jan 22 in Medicinal Chemistry by TahliaEvatt8 (2.2k points)

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1 answer 70 views

How can we use the knowledge of the chemical makeup of different viruses to design drugs that target their specific characteristics and prevent infection?

asked Jan 22 in Medicinal Chemistry by RobertBousqu (1.5k points)

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1 answer 91 views

How does the CYP3A4 enzyme affect the metabolism and potential interactions of commonly prescribed drugs in the treatment of cardiovascular disease?

asked Jan 22 in Medicinal Chemistry by MervinBowden (2.1k points)

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1 answer 79 views

How can we use the knowledge of the chemical makeup of different viruses to design drugs that target their specific characteristics and prevent infection?

asked Jan 22 in Medicinal Chemistry by SterlingIsr (1.7k points)

Recent questions in Medicinal Chemistry

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