Recent questions in Medicinal Chemistry

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How can chemists modify the chemical structure of existing antibiotics to overcome drug-resistant bacterial infections like MRSA (Methicillin-Resistant Staphylococcus Aureus)?

asked Feb 5 in Medicinal Chemistry by AddieFrayne (1.7k points)

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1 answer 47 views

How can chemists design new drugs that target specific receptors in the gastrointestinal tract to treat conditions such as irritable bowel syndrome and inflammatory bowel disease?

asked Feb 5 in Medicinal Chemistry by Juliana93U49 (2.3k points)

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1 answer 31 views

How can small molecules be designed and modified to target specific metabolic pathways in the treatment of metabolic disorders such as diabetes or obesity?

asked Feb 5 in Medicinal Chemistry by JordanChun58 (2.3k points)

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How can small molecule inhibitors target specific immune cells and modulate their activity to treat autoimmune diseases?

asked Feb 5 in Medicinal Chemistry by HenryCharles (2.0k points)

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How can small molecule inhibitors be designed to target specific molecules involved in the pathogenesis of autoimmune diseases such as rheumatoid arthritis?

asked Feb 5 in Medicinal Chemistry by JordanChun58 (2.3k points)

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How can small molecule inhibitors be designed and synthesized to target specific inflammatory pathways and effectively treat inflammatory diseases such as rheumatoid arthritis or Crohn's disease?

asked Feb 5 in Medicinal Chemistry by MeaganCramp (1.8k points)

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How can small molecule inhibitors be designed and synthesized to selectively target autoimmune disease-causing immune cells while sparing healthy cells in the body?

asked Feb 5 in Medicinal Chemistry by AudraNowlin6 (2.2k points)

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How can researchers modify existing antibiotics to combat drug-resistant bacteria and what are the challenges associated with this approach?

asked Feb 5 in Medicinal Chemistry by YOKIva496594 (2.6k points)

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1 answer 48 views

How can researchers develop a new treatment for cardiovascular diseases that effectively targets specific pathways or receptors within the body while avoiding potential off-target effects that may cause harm to the patient? What specific chemical compounds or modifications could be used to achieve this goal, and how can their efficacy and safety be tested in preclinical and clinical studies?

asked Feb 5 in Medicinal Chemistry by TrevorE07525 (2.2k points)

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1 answer 37 views

How can pharmacogenetics be used to predict an individual's response to a specific drug and optimize drug therapy for that individual?

asked Feb 5 in Medicinal Chemistry by ElyseY075419 (1.7k points)

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How can one design a drug that targets a specific genetic mutation and corrects the abnormal function of the associated protein, in individuals affected by genetic disorders? Provide a step-by-step approach to designing such a drug, considering factors such as protein structure, ligand identification and optimization, and pharmacokinetics.

asked Feb 5 in Medicinal Chemistry by RobynButz517 (1.9k points)

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1 answer 37 views

How can novel small molecule inhibitors be designed and synthesized to target specific molecular pathways involved in the development of respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD)?

asked Feb 5 in Medicinal Chemistry by EdytheEwk100 (2.6k points)

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1 answer 35 views

How can novel drug molecules be designed and synthesized to effectively target specific molecular pathways involved in the development and progression of cardiovascular diseases such as atherosclerosis, heart failure, and hypertension?

asked Feb 5 in Medicinal Chemistry by DeanI7567799 (2.2k points)

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How can new drugs be designed to effectively target and treat neurological disorders such as Alzheimer's and Parkinson's disease while minimizing unwanted side effects and toxicity to the patient's body?

asked Feb 5 in Medicinal Chemistry by WilburGuerre (2.3k points)

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1 answer 39 views

How can natural compounds extracted from plants be modified to develop effective treatments for gastrointestinal diseases such as Crohn's and ulcerative colitis? What specific chemical modifications need to be made to enhance bioavailability and efficacy of these compounds as potential medications for digestive disorders?

asked Feb 5 in Medicinal Chemistry by AlexK0785479 (1.8k points)

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1 answer 42 views

How can molecular modification be used to improve the efficacy and/or reduce the side effects of current treatments for conditions such as inflammatory bowel disease and acid reflux?

asked Feb 5 in Medicinal Chemistry by Rudy59684212 (1.8k points)

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1 answer 51 views

How can modifications to an existing molecule increase its efficacy and reduce its toxicity in the development of new treatments for autoimmune diseases?

asked Feb 5 in Medicinal Chemistry by KristopherMi (2.1k points)

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1 answer 36 views

How can medicinal chemists utilize structure-activity relationship (SAR) studies to design new small molecule drugs that selectively target specific immune cells involved in autoimmune diseases, while minimizing off-target effects and toxicity?

asked Feb 5 in Medicinal Chemistry by BYUBlake479 (2.0k points)

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How can medicinal chemists modify existing antibiotics to create new compounds that are effective against drug-resistant bacteria strains, specifically targeting the mechanisms that these bacteria use to resist traditional antibiotics?

asked Feb 5 in Medicinal Chemistry by CarltonWoote (1.7k points)

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1 answer 31 views

How can medicinal chemists modify existing antibiotics to combat drug-resistant bacteria strains?

asked Feb 5 in Medicinal Chemistry by CassieClopto (2.4k points)

Recent questions in Medicinal Chemistry

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