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How do genetic variations affect the metabolism and effectiveness of drugs used in the treatment of diabetes, and what are the implications of this for personalized medicine?
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Feb 13
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Medicinal Chemistry
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ValeriaStrom
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How can we design a polymer-based drug delivery system that can effectively deliver a specific drug to a target site in the body while minimizing side-effects and maximizing therapeutic efficacy?
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Feb 12
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Polymer Chemistry
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WilheminaMea
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How to design a feasible and economical system that produces pure hydrogen fuel with a high yield while minimizing energy consumption, by utilizing the principles of chemical engineering and taking into account the potential impact on the environment?
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Feb 12
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Chemical engineering
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GlendaNester
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How does the doping concentration of a conductive polymer affect its electrical conductivity and mechanical properties, and what is the optimal doping level for use in flexible electronics?
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Feb 12
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Materials Chemistry
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Osvaldo14767
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What specific biomaterial properties should be considered and investigated for their potential use in tissue engineering, and how can these properties be optimized to enhance tissue regeneration and integration?
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Feb 13
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Materials Chemistry
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MarquisMonte
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How can we design drugs to target specific genetic mutations responsible for causing neurodegenerative disorders, such as Huntington's disease, while minimizing off-target effects?
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Feb 12
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Medicinal Chemistry
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LeannaDoming
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36
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How can we develop eco-friendly methods for the synthesis of metal nanoparticles using renewable resources as reducing agents and stabilizers, while minimizing the use of toxic and hazardous chemicals commonly used in traditional synthesis methods?
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Feb 12
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Materials Chemistry
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SammieToohey
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How can we design new molecules that specifically target and inhibit the COX-2 enzyme to effectively treat inflammatory diseases without causing unwanted side effects?
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Feb 12
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Medicinal Chemistry
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KatherinaI21
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How have environmental regulations affected the use of lead in gasoline and its impact on air quality?
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Feb 13
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Environmental Chemistry
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AubreyWoore
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How can we design a safe and efficient system for the storage and transportation of highly reactive and flammable chemicals in the chemical industry while minimizing the risk of accidents and/or exposure to toxic substances?
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Feb 12
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Chemical engineering
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Von968188852
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What is the role of DNA polymerases during DNA replication and how do they ensure the accuracy of DNA synthesis? Provide specific examples of proofreading mechanisms used by DNA polymerases to maintain the integrity of the genetic code.
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Feb 12
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BioChemistry
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DominickPlum
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How to design a production system for lubricants that meets the specified requirements including process flow, raw materials selection, processing conditions, quality control measures and cost optimization?
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Feb 12
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Chemical engineering
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DanaPittmann
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What is the effect of the popular pesticide glyphosate on human health when ingested through food? What is the mechanism of toxicity and how can it be mitigated?
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Feb 13
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Environmental Chemistry
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ArnulfoWall
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How does the regulation of glycolysis and gluconeogenesis differ in the liver compared to other tissues in the body? Provide examples of signaling pathways and enzymes involved in this regulation.
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Feb 13
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BioChemistry
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CesarSpragg2
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What are the structural differences between DNA and RNA, and how do these differences affect their biological functions?
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Feb 12
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Organic Chemistry
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CelsaTroiano
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How do different chemical functional groups affect the electronic properties and reactivity of surfaces in catalytic reactions, as determined by density functional theory calculations?
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Feb 12
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Computational Chemistry
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Leif76792351
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How does doping graphene with nitrogen affect its electronic properties and conductivity?
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Feb 12
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Materials Chemistry
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BuckY7205505
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1
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47
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How can we design a drug that targets the synaptic vesicle glycoprotein 2A (SV2A) to treat neurological disorders such as epilepsy, without causing toxicity or unwanted side effects?
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Feb 12
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Medicinal Chemistry
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HoracioMott0
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1.8k
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39
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How can we design and synthesize small molecule inhibitors that selectively target autoimmune disease-causing immune cells and suppress their activity without affecting healthy cells in the body?
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Feb 12
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Medicinal Chemistry
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LinetteWaldo
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32
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What is the net ATP gained during glycolysis, and how is it generated?
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Feb 13
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BioChemistry
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JeanetteOffi
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