0 votes
22 views
ago in Chemical synthesis by (139k points)
What is the appropriate reaction conditions (such as temperature, pressure and catalyst) required for the successful preparation of 2-chloro-4-nitroaniline from aniline and chlorine gas through the process of Chemical synthesis?

1 Answer

0 votes
ago by (139k points)
The preparation of 2-chloro-4-nitroaniline from aniline and chlorine gas can be achieved through a two-step process:1. Nitration of aniline to form 4-nitroaniline:Aniline  C6H5NH2  is first nitrated to form 4-nitroaniline  C6H4 NO2 NH2 . This reaction requires a mixture of concentrated sulfuric acid  H2SO4  and concentrated nitric acid  HNO3  as the nitrating agents. The reaction is carried out at low temperatures  0-5C  to minimize the formation of undesired by-products.2. Chlorination of 4-nitroaniline to form 2-chloro-4-nitroaniline:4-nitroaniline is then chlorinated using chlorine gas  Cl2  to form 2-chloro-4-nitroaniline  C6H3Cl NO2 NH2 . This reaction requires a catalyst, such as cupric chloride  CuCl2  or iron III  chloride  FeCl3 , to facilitate the electrophilic aromatic substitution. The reaction is typically carried out at room temperature  20-25C  and under atmospheric pressure.In summary, the appropriate reaction conditions for the successful preparation of 2-chloro-4-nitroaniline from aniline and chlorine gas are:1. Nitration step:- Temperature: 0-5C- Nitrating agents: Concentrated H2SO4 and HNO32. Chlorination step:- Temperature: 20-25C  room temperature - Pressure: Atmospheric pressure- Catalyst: Cupric chloride  CuCl2  or iron III  chloride  FeCl3
Welcome to Sarvan Science Q&A, where you can ask questions and receive answers from other members of the community.
...