The photochemical behavior of chiral molecules differs from that of their achiral counterparts due to their unique structural properties. Chiral molecules are non-superimposable mirror images of each other, known as enantiomers. They have the same chemical composition but differ in the spatial arrangement of their atoms. This difference in spatial arrangement leads to distinct interactions with light, specifically with circularly polarized light.When chiral molecules interact with circularly polarized light, they can absorb left-handed L or right-handed R circularly polarized light differently. This phenomenon is known as circular dichroism CD . Achiral molecules, on the other hand, do not exhibit this property as they do not have a specific handedness. The difference in absorption of circularly polarized light by chiral molecules can lead to different photochemical reactions, such as isomerization, dissociation, or electron transfer, depending on the specific molecule and its environment.This unique photochemical behavior of chiral molecules can be utilized in chiral separation techniques. One such technique is the use of circularly polarized light to selectively excite one enantiomer over the other, leading to different photochemical reactions or products. This can result in the formation of diastereomers, which are easier to separate due to their different physical and chemical properties.Another technique is the use of chiral stationary phases in chromatography, where the chiral selector interacts differently with each enantiomer, leading to different retention times and allowing for their separation. Chiral photochemical reactions can also be used to modify the chiral selector, enhancing its selectivity and improving the separation process.In summary, the photochemical behavior of chiral molecules differs from that of their achiral counterparts due to their unique interactions with circularly polarized light. This difference can be exploited in chiral separation techniques, such as selective photochemical reactions and chiral chromatography, to effectively separate enantiomers.