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How does the addition of a strong base affect the ionization of acetic acid? Provide a detailed explanation of the resulting shift in equilibrium and the effect on pH.

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The addition of a strong base to a solution containing acetic acid  a weak acid  will affect the ionization of acetic acid by shifting the equilibrium of the reaction and increasing the pH of the solution. To understand this, let's first look at the ionization reaction of acetic acid and the concept of equilibrium.Acetic acid  CH3COOH  is a weak acid, meaning it does not completely ionize in water. When it is dissolved in water, it undergoes a partial ionization reaction:CH3COOH  aq  + H2O  l   CH3COO-  aq  + H3O+  aq In this reaction, acetic acid donates a proton  H+  to water, forming the acetate ion  CH3COO-  and the hydronium ion  H3O+ . Since this is an equilibrium reaction, both the reactants and products are present in the solution.Now, let's consider the addition of a strong base, such as sodium hydroxide  NaOH , to the acetic acid solution. Sodium hydroxide is a strong base, meaning it completely dissociates in water:NaOH  aq   Na+  aq  + OH-  aq The hydroxide ions  OH-  from the strong base will react with the hydronium ions  H3O+  present in the acetic acid solution:OH-  aq  + H3O+  aq   2H2O  l This reaction removes hydronium ions from the solution, causing a decrease in the concentration of H3O+ ions. According to Le Chatelier's principle, when a change is made to a system in equilibrium, the system will shift to counteract that change. In this case, the decrease in H3O+ concentration will cause the equilibrium of the acetic acid ionization reaction to shift to the right, producing more CH3COO- and H3O+ ions:CH3COOH  aq  + H2O  l   CH3COO-  aq  + H3O+  aq As a result, more acetic acid molecules will ionize to compensate for the loss of hydronium ions. This shift in equilibrium will continue until the strong base is completely neutralized by the weak acid.The overall effect of adding a strong base to the acetic acid solution is an increase in pH. As the strong base reacts with and removes hydronium ions from the solution, the concentration of H3O+ ions decreases, leading to a higher pH value. The solution will become less acidic and more basic as the strong base is added.
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