0 votes
21 views
ago in BioChemistry by (430 points)
What is the effect of pH on the activity of the enzyme catalase in breaking down hydrogen peroxide?

1 Answer

0 votes
ago by (330 points)
The activity of the enzyme catalase in breaking down hydrogen peroxide is affected by pH, as with most enzymes. Catalase is a biological catalyst that accelerates the decomposition of hydrogen peroxide  H2O2  into water  H2O  and oxygen  O2  without being consumed in the reaction. The enzyme is found in various organisms, including bacteria, plants, and animals, and plays a crucial role in protecting cells from oxidative damage caused by hydrogen peroxide.The effect of pH on catalase activity can be explained by the fact that enzymes have an optimal pH range in which they function most efficiently. This optimal pH range is determined by the enzyme's structure and the specific amino acids involved in catalysis.For catalase, the optimal pH range is typically between 7 and 7.5, which is close to neutral pH. Within this range, the enzyme exhibits its highest activity and efficiently breaks down hydrogen peroxide. However, when the pH deviates from this optimal range, the enzyme's activity decreases.At lower pH values  acidic conditions , the excess of hydrogen ions  H+  can lead to protonation of the amino acid residues in the enzyme's active site, disrupting the enzyme's structure and its ability to bind to the substrate  hydrogen peroxide . This results in a decrease in catalase activity.At higher pH values  alkaline conditions , the excess of hydroxide ions  OH-  can lead to deprotonation of the amino acid residues in the enzyme's active site, also disrupting the enzyme's structure and its ability to bind to the substrate. This, too, results in a decrease in catalase activity.In summary, the activity of the enzyme catalase in breaking down hydrogen peroxide is affected by pH, with optimal activity occurring at a near-neutral pH range of 7 to 7.5. Deviations from this optimal pH range, either acidic or alkaline, can lead to a decrease in catalase activity due to structural changes in the enzyme's active site.
Welcome to Sarvan Science Q&A, where you can ask questions and receive answers from other members of the community.
...