In coordination chemistry of transition metals, the stability of a coordination compound is influenced by various factors, including the size of the ligands. Increasing the size of the ligands can have several effects on the stability of a coordination compound:1. Steric hindrance: Larger ligands can cause steric hindrance, which may lead to a decrease in the stability of the coordination compound. Steric hindrance occurs when the bulky ligands are too close to each other, causing repulsion between their electron clouds. This repulsion can destabilize the compound, making it more susceptible to decomposition or substitution reactions.2. Chelate effect: If the larger ligands are multidentate capable of binding to the metal center through multiple donor atoms , they can form chelate rings with the metal center. Chelate rings can increase the stability of a coordination compound due to the chelate effect, which is the increased stability of a compound when a metal ion is bonded to two or more atoms of a ligand in a ring structure. This is because the formation of chelate rings reduces the entropy change during complex formation, making the overall reaction more favorable.3. Electronic effects: The size of the ligands can also affect the electronic properties of the coordination compound. Larger ligands may have different electron-donating or electron-withdrawing abilities compared to smaller ligands, which can influence the stability of the compound. For example, strong electron-donating ligands can increase the electron density around the metal center, making it more susceptible to nucleophilic attack and potentially decreasing the stability of the compound.4. Crystal field stabilization energy CFSE : The size of the ligands can influence the crystal field stabilization energy, which is the energy difference between the metal-ligand interactions in the complex and the interactions in the separated ions. Larger ligands may cause a weaker crystal field, leading to a smaller CFSE and potentially a less stable compound.In summary, increasing the size of the ligands can have both positive and negative effects on the stability of a coordination compound, depending on the specific ligands and metal center involved. The overall stability of the compound will depend on a balance of these factors.