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How do certain chemical modifications in precursor RNA molecules affect splice site selection and ultimately impact the final mRNA isoforms produced during RNA processing?

asked Jan 31 in BioChemistry by LashawnGoose (310 points)

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How do certain amino acid sequences affect the folding mechanism of proteins, as observed through molecular dynamics simulations, and how can this information be used to understand and design more effective protein therapeutics?

asked Jan 31 in Computational Chemistry by IsabellaSher (790 points)

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How does the accumulation of ceramides contribute to insulin resistance and Type 2 Diabetes Mellitus in lipid metabolism?

asked Jan 31 in BioChemistry by Alyce51K2334 (440 points)

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What are the specific properties of ceramics that make them suitable for use in high-temperature applications, and how can these properties be manipulated to improve their performance in extreme environments?

asked Jan 31 in Materials Chemistry by PaulinaStran (210 points)

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What are the key material properties that make ceramics suitable for high-temperature applications, and how can these properties be optimized or improved through chemical and material design?

asked Jan 31 in Materials Chemistry by RodneyC3252 (310 points)

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What are the key properties and structural characteristics that make ceramics suitable for high-temperature applications, and how do these properties compare to those of other materials used at high temperatures?

asked Jan 31 in Materials Chemistry by ErnestoBrook (490 points)

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How do the properties of ceramics change at high temperatures, and what makes them suitable for use in high-temperature applications such as gas turbine engines and furnace linings?

asked Jan 31 in Materials Chemistry by GayePetheric (310 points)

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How do cells recognize and selectively degrade specific proteins within the cell? Describe the molecular mechanisms that underlie protein degradation and the various pathways involved.

asked Jan 31 in BioChemistry by KeithMartin8 (230 points)

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What are the lipid components of cell membranes and how do they contribute to the membrane's structure and function?

asked Jan 31 in BioChemistry by SofiaDenison (870 points)

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What parameters affect catalytic activity and selectivity in the hydrogenation of ethylene to ethane using a platinum-based catalyst?

asked Jan 31 in Physical Chemistry by Barrett98Q2 (190 points)

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What is the effect of different types of catalysts on the reaction rate of the decomposition of hydrogen peroxide?

asked Jan 31 in Chemical kinetics by JohnieHatten (390 points)

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What is the effect of different types of catalysts (such as homogenous and heterogeneous catalysts) on the rate of a specific reaction, and how can this be practically applied in industrial processes?

asked Jan 31 in Physical Chemistry by NevaSturgeon (270 points)

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What is the effect of catalysts on the rate of a chemical reaction in terms of activation energy? And, using the Arrhenius equation, calculate the activation energy for the catalyzed and non-catalyzed reactions and compare the two values.

asked Jan 31 in Physical Chemistry by KatlynSwan2 (430 points)

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Describe the coordination geometry and the type of ligands involved in the active site of the metalloenzyme catalase, which uses a heme group to convert hydrogen peroxide to water and oxygen. How does the nature of the ligands and the coordination geometry contribute to the enzyme's catalytic activity?

asked Jan 31 in Coordination Chemistry by MargretSheph (470 points)

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How does the regulation of fatty acid oxidation through the activity of carnitine palmitoyltransferase 1 (CPT1) in the liver impact lipid metabolism and transport in the body?

asked Jan 31 in BioChemistry by LinneaSux114 (430 points)

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What is the role of carnitine in lipid metabolism and how does its deficiency lead to lipid storage disorders?

asked Jan 31 in BioChemistry by Twyla390140 (590 points)

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What is the difference in reactivity between carboxylic acids and acid chlorides towards nucleophilic substitution reactions, and what factors affect their reactivity?

asked Jan 31 in Organic Chemistry by MaeWing7071 (570 points)

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1 answer 67 views

What is the role of the metal ion in the active site of the metalloenzyme carbonic anhydrase, and how does this facilitate the enzyme's function of catalyzing the hydration of carbon dioxide to bicarbonate ion?

asked Jan 31 in Coordination Chemistry by HungN507681 (370 points)

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How does the coordination chemistry of the metalloenzyme, carbonic anhydrase, contribute to its catalytic activity?

asked Jan 31 in Coordination Chemistry by AprilCutlack (490 points)

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Identify and explain the role of the metal ion in the active site of the metalloenzyme carbonic anhydrase, and discuss how its coordination environment affects its catalytic activity.

asked Jan 31 in Coordination Chemistry by VUYKaren8493 (250 points)

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