Recent questions in Medicinal Chemistry

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How do the molecular properties of a drug affect its pharmacokinetics in the body and what factors should be considered in order to optimize the absorption, distribution, metabolism, and elimination of the drug for effective therapeutic outcomes?

asked Feb 21 in Medicinal Chemistry by TroyWitcher8 (2.1k points)

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What molecular features of a drug make it effective in targeting a specific receptor or enzyme? Provide an example of a drug targeting a specific receptor or enzyme and explain its molecular interactions with the target site.

asked Feb 21 in Medicinal Chemistry by RobtGranier (2.1k points)

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How does the mode of action of a particular drug in the body affect its pharmacodynamic properties and potential as a therapeutic agent?

asked Feb 21 in Medicinal Chemistry by FionaGreenbe (1.8k points)

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How does the metabolism of drugs in the body affect their efficacy and toxicity in treating specific diseases?

asked Feb 20 in Medicinal Chemistry by EdwinStambau (2.4k points)

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How does the metabolism of drugs in the body affect their efficacy and potential adverse effects? Provide specific examples of some drugs and their metabolites, and explain the role of enzymes and pathways involved in drug metabolism.

asked Feb 20 in Medicinal Chemistry by YukikoDalgle (1.6k points)

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How does the metabolic profile of a drug affect its efficacy and toxicity in the human body?

asked Feb 20 in Medicinal Chemistry by LorrineA1626 (1.6k points)

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How does the metabolic pathway affect the efficacy and toxicity of an anti-inflammatory drug in the human body?

asked Feb 20 in Medicinal Chemistry by KarmaJ651641 (1.9k points)

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How does the metabolic pathway of a particular drug affect its efficacy and potential side effects in the body?

asked Feb 20 in Medicinal Chemistry by DeanneMack98 (2.1k points)

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1 answer 84 views

How does the metabolic pathway of a drug affect its efficacy and toxicity in the human body? Provide examples of drugs that undergo extensive metabolism and discuss how their metabolites contribute to their effects and side effects.

asked Feb 20 in Medicinal Chemistry by BriannaFauld (1.6k points)

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How does the metabolic breakdown of a specific medication affect its effectiveness and potential side effects in the body?

asked Feb 20 in Medicinal Chemistry by VickeyBatema (1.9k points)

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How does the mechanism of action of a chosen drug in the body affect its therapeutic effectiveness and potential side effects? Provide a detailed explanation using relevant pharmacodynamic principles and examples.

asked Feb 20 in Medicinal Chemistry by NicholeBlade (2.1k points)

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1 answer 81 views

What are the main mechanisms of antibacterial drug resistance in gram-positive bacteria, and how can medicinal chemists develop new antibiotics to combat these mechanisms?

asked Feb 20 in Medicinal Chemistry by AlishaGuy35 (2.5k points)

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1 answer 78 views

How does the liver affect the metabolism of different drugs in the body, and what are the specific enzymes involved in this process? Provide a detailed explanation and include examples of drugs that are primarily metabolized by the liver.

asked Feb 20 in Medicinal Chemistry by ImaSimmons79 (2.3k points)

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How does the liver's Phase I and Phase II metabolic reactions affect the efficacy and toxicity of a drug in the body?

asked Feb 20 in Medicinal Chemistry by EmerySynan65 (1.8k points)

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How does the liver metabolism affect the pharmacokinetics of a drug being administered for the treatment of a particular disease?

asked Feb 20 in Medicinal Chemistry by Precious09K0 (2.0k points)

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How does the liver metabolize commonly used pain relievers, such as acetaminophen or ibuprofen, and what chemical reactions are involved in this process? How do changes in liver function or genetic variations affect the metabolism of these drugs?

asked Feb 20 in Medicinal Chemistry by CornellNicho (2.1k points)

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1 answer 71 views

How does the liver metabolize drugs and what factors affect drug metabolism in the body?

asked Feb 20 in Medicinal Chemistry by Danny16L1758 (1.6k points)

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1 answer 84 views

What are the key molecular targets and mechanisms employed in the drug design strategies for treating metabolic disorders such as diabetes and obesity, and how can these drugs maximize efficacy and minimize side effects?

asked Feb 20 in Medicinal Chemistry by CecileHollin (2.3k points)

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How does the interaction between Warfarin (an anticoagulant drug) and Aspirin impact their effectiveness in treating blood clotting disorders?

asked Feb 20 in Medicinal Chemistry by AleidaSeifer (1.7k points)

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How does the interaction between the anti-coagulant drug warfarin and the antibiotic ciprofloxacin affect the therapeutic efficacy and potential side effects of both drugs?

asked Feb 20 in Medicinal Chemistry by CatherineMcc (2.5k points)

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