Recent questions in Medicinal Chemistry

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How does genetic variation affect the metabolism and effectiveness of clopidogrel, a commonly used antiplatelet drug, and what are the implications for personalized medicine?

asked Feb 13 in Medicinal Chemistry by CornellNicho (2.1k points)

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How does genetic variability affect the metabolization and efficacy of anti-cancer drugs in patients with different CYP2D6 genotypes?

asked Feb 13 in Medicinal Chemistry by CandyMusquit (1.8k points)

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How does genetic variability influence drug response and efficacy in the treatment of cancer patients, specifically for the chemotherapy drug cisplatin?

asked Feb 13 in Medicinal Chemistry by MonteEsteban (1.8k points)

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How does the drug doxorubicin work in treating cancer, and what specific cellular processes and pathways does it target?

asked Feb 12 in Medicinal Chemistry by MargueriteSa (2.1k points)

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How do different metabolites of a specific drug affect its potency and toxicity in the body, and how can medicinal chemists use this information to optimize drug design and minimize unwanted side effects?

asked Feb 12 in Medicinal Chemistry by GabrielCantu (1.6k points)

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How do different genetic variations affect the response of a certain drug in a specific patient population and what are the implications for personalized drug therapy in the field of medicinal chemistry?

asked Feb 12 in Medicinal Chemistry by PhilipPrisco (1.9k points)

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How do different drug combinations affect the absorption and metabolism of each other in the body?

asked Feb 12 in Medicinal Chemistry by RudyMms5536 (1.8k points)

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How can we develop new treatments for skin diseases using knowledge of the chemical properties of compounds found in natural sources such as plants and microorganisms?

asked Feb 12 in Medicinal Chemistry by CandyDemaio (2.3k points)

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1 answer 68 views

What are the most effective strategies for developing new treatments for respiratory diseases using medicinal chemistry techniques?

asked Feb 12 in Medicinal Chemistry by Phillipp57B1 (2.3k points)

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How can we develop new treatments for gastrointestinal diseases by designing drugs that target the acid secretion pathway and reduce the harmful effects of excess stomach acid?

asked Feb 12 in Medicinal Chemistry by FrederickTho (1.9k points)

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How can we develop new antiviral treatments that are both effective and safe for patients?

asked Feb 12 in Medicinal Chemistry by MaximoVardon (1.9k points)

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How can we develop a novel drug delivery system for the treatment of respiratory diseases using targeted therapies?

asked Feb 12 in Medicinal Chemistry by AguedaD83620 (2.6k points)

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1 answer 65 views

How can we develop a new treatment for eczema using medicinal chemistry principles? Specifically, what specific molecules or compounds could be used to target the underlying mechanisms of eczema and alleviate its symptoms?

asked Feb 12 in Medicinal Chemistry by JEAMolly3713 (2.3k points)

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1 answer 65 views

How can we develop a more effective and targeted treatment for autoimmune diseases by utilizing the principles of medicinal chemistry, such as drug design and optimization?

asked Feb 12 in Medicinal Chemistry by JacquieGuzzi (2.2k points)

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1 answer 65 views

How can we design small-molecule drugs to target the root cause of genetic disorders by correcting or restoring the function of mutated proteins, while avoiding off-target effects that can lead to toxicity or other side effects?

asked Feb 12 in Medicinal Chemistry by NicholeBueno (1.8k points)

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1 answer 32 views

How can we design small molecules as potential drugs to target specific inflammatory pathways in the human body while minimizing off-target effects?

asked Feb 12 in Medicinal Chemistry by Brigette3451 (1.8k points)

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How can we design small molecule inhibitors of viral protein targets to prevent the replication of the influenza virus?

asked Feb 12 in Medicinal Chemistry by BuckY7205505 (1.7k points)

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1 answer 53 views

How can we design small molecule drugs targeting specific respiratory disease pathways, such as bronchoconstriction or airway inflammation, using medicinal chemistry approaches?

asked Feb 12 in Medicinal Chemistry by NorineFelici (1.8k points)

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1 answer 34 views

How can we design novel antiviral agents that target viral enzymes with high specificity and potency, but have minimal off-target effects on host cell proteins?

asked Feb 12 in Medicinal Chemistry by AudraNowlin6 (2.2k points)

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1 answer 56 views

How can we design new molecules that specifically target and inhibit the COX-2 enzyme to effectively treat inflammatory diseases without causing unwanted side effects?

asked Feb 12 in Medicinal Chemistry by KatherinaI21 (1.8k points)

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