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How can we design a drug that targets the protein kinase enzyme without affecting other non-targeted enzymes in the body, and what are the chemical properties that can optimize the drug's binding affinity to the enzyme's active site?

asked Feb 12 in Medicinal Chemistry by MirtaBly0080 (2.0k points)

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What is the specific chemical structure of RNA and how do the base pairings differ from DNA? How does the structure of RNA contribute to its function within the cell?

asked Feb 14 in BioChemistry by AnjaAbt20068 (2.0k points)

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How does the coordination chemistry of metalloenzymes and metalloproteins affect their biological activity and function? Discuss with examples.

asked Feb 12 in Coordination Chemistry by AnjaAbt20068 (2.0k points)

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How can the sensitivity and selectivity of a sensor based on polymer matrix be improved for detecting a specific analyte in a complex matrix?

asked Feb 10 in Polymer Chemistry by DeloresQ3217 (1.6k points)

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What is the role of DNA polymerase in DNA replication, and how does its proofreading function ensure the accuracy of the DNA replication process?

asked Feb 12 in BioChemistry by EllenColling (2.0k points)

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How does coordination chemistry contribute to the understanding of the catalytic mechanisms of metalloenzymes and metalloproteins? Provide specific examples and explain the key coordination properties that influence enzymatic activity.

asked Feb 12 in Coordination Chemistry by DannieGuf001 (2.3k points)

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How can we design a drug that specifically targets the enzyme responsible for a certain disease state, while avoiding interference with other enzymes or receptors in the body?

asked Feb 12 in Medicinal Chemistry by HildredU3922 (1.9k points)

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1 answer 119 views

How does cholesterol affect the fluidity of the cell membrane? Provide a detailed explanation with examples.

asked Feb 12 in BioChemistry by AdaFennescey (1.8k points)

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1 answer 118 views

How can we use computational methods to predict the adsorption properties of metal-organic frameworks?

asked Feb 12 in Computational Chemistry by TimNakamura (2.0k points)

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How can the synthesis and characterization of new materials be optimized to improve the efficiency of solar cells?

asked Feb 11 in Materials Chemistry by KeriLundberg (2.0k points)

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What are the chemical pollutants commonly used in farming practices and how do they impact the environment in the long term? Can alternative farming techniques be used to reduce the negative impact of chemical pollutants on soil, water, and air quality?

asked Feb 12 in Environmental Chemistry by AlishaGolder (1.9k points)

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How does the coordination chemistry of metalloenzymes and metalloproteins affect their catalytic activity? Provide specific examples of metalloenzymes/proteins and their coordination chemistry that illustrate this phenomenon.

asked Feb 12 in Coordination Chemistry by WandaBalsill (1.3k points)

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1 answer 93 views

How does the signaling molecule, epinephrine, trigger the activation of adenylyl cyclase and subsequent cAMP production in the signal transduction pathway?

asked Feb 13 in BioChemistry by JaysonMcKenn (2.3k points)

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How can we design drugs that specifically target the protein structure of the SARS-CoV-2 virus to inhibit its replication and prevent the spread of COVID-19?

asked Feb 12 in Medicinal Chemistry by PhillipPugli (2.1k points)

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How can we design a drug that targets and inhibits the replication of the Zika virus, while not affecting healthy human cells?

asked Feb 12 in Medicinal Chemistry by PearlEaston (2.3k points)

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What are the pharmacological activities of the natural product curcumin and what structural features contribute to these activities?

asked Feb 12 in Medicinal Chemistry by TiffaniWymar (1.6k points)

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1 answer 95 views

What is the specific chemical reaction that occurs during DNA replication, and how does the cell ensure that errors in the DNA sequence are corrected during the replication process?

asked Feb 13 in BioChemistry by TVMBeulah703 (2.4k points)

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1 answer 191 views

How can the process for the production of a specific specialty chemical be optimized to increase the yield and efficiency, while also minimizing waste and environmental impact?

asked Feb 10 in Chemical engineering by EddieDurack (2.2k points)

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1 answer 186 views

How can the properties of liquid crystals be optimized to enhance the display quality of an LCD device?

asked Feb 10 in Materials Chemistry by ErikGendron8 (1.4k points)

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1 answer 99 views

How can we design new anti-inflammatory drugs that have improved efficacy and fewer side effects compared to the current treatments?

asked Feb 12 in Medicinal Chemistry by KitRatley759 (1.9k points)

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