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How can we design drugs that specifically target and inhibit the growth of gram-negative bacteria, such as E. coli or P. aeruginosa, while leaving the beneficial gut microbiota unharmed?
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Feb 12
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Medicinal Chemistry
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JonelleCouls
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How do G protein-coupled receptors (GPCRs) initiate signal transduction pathways in cells? Discuss the biochemical mechanism involved in the activation of GPCRs and the downstream signaling events that follow.
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Feb 13
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BioChemistry
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How can the structure and composition of drug delivery systems be optimized to improve efficacy and decrease potential side effects?
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Feb 10
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Medicinal Chemistry
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KenOlvera57
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How can the stimulus-responsive behavior of a polymer-based smart material be optimized for a specific application, such as drug delivery or sensing?
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Feb 10
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Polymer Chemistry
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RosemarieKin
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How does the crystal field theory explain the color of transition metal complexes and how can this theory be used to predict the color of a coordination compound based on its ligand field?
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Feb 12
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Coordination Chemistry
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DominickArel
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How does crystal field theory explain the color of transition metal complexes? Provide an example of a complex and explain how its color can be predicted based on its electronic structure and crystal field splitting.
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Feb 12
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Coordination Chemistry
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TaneshaDoss0
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How can we design a drug that specifically targets the opioid receptor to treat chronic pain, while avoiding activation of other receptors in the body that may cause harmful side effects?
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Feb 12
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Medicinal Chemistry
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ElviaM111599
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How does cholesterol affect the fluidity of cell membranes and why is it important for maintaining cellular function?
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Feb 12
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BioChemistry
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CharmainHers
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How does the chemical modification of RNA molecules, such as splicing and editing, affect the functions and activities of proteins they encode, and how can this information be used in drug development and disease treatment?
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Feb 12
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BioChemistry
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DeneseSteinm
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What specific amino acid residues in a DNA-binding protein interact with specific nucleotide bases in double-stranded DNA, and what types of interactions (e.g. hydrophobic, electrostatic) are involved in regulating transcriptional activity?
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Feb 13
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BioChemistry
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GraceChaves1
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How can the properties of a semiconductor material be optimized to improve the performance and efficiency of electronic devices such as solar cells and transistors?
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Feb 10
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Materials Chemistry
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RaulGalway75
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How can the synthesis of metal-organic frameworks be optimized to improve crystallinity, stability, and yield?
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Feb 11
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Materials Chemistry
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CDEMargherit
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How can the synthesis and characterization of coordination compounds be used in the development of new chemotherapy drugs for cancer treatment? Provide a specific example of a coordination compound that has shown promising results in cancer treatment and explain how it works on a molecular level.
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Feb 11
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Coordination Chemistry
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EvaO88610769
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How can we design a chemical system for the efficient and cost-effective production of high-quality paints and coatings with environmentally friendly components?
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Feb 12
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Chemical engineering
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WyattBriones
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How can we design a polymer-based optical material that exhibits high refractive index and low optical dispersion?
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Feb 12
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Polymer Chemistry
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How can we design antiviral drugs that target specific viral proteins while minimizing off-target effects on human proteins?
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Feb 12
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Medicinal Chemistry
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FletaStepp73
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How does controlling the pH of the solution affect the adsorption of proteins on solid surfaces?
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Feb 12
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Surface Chemistry
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How can the synthesis of polyethylene from ethylene monomer be optimized to yield a higher molecular weight polymer?
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Feb 11
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Chemical synthesis
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BlaineBeasle
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How can the synthesis and characterization of a novel material be optimized for efficient removal of heavy metals from contaminated water sources?
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Feb 11
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Materials Chemistry
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ElyseY075419
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What is the difference in coordination chemistry between metallofullerenes and metalloclusters, and how does this impact their properties and potential applications in industries such as pharmaceuticals and electronics?
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Feb 12
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Coordination Chemistry
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TroyWitcher8
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