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How can we design a drug that specifically targets the enzymes responsible for inflammation in the body, without affecting other enzymes that play important roles in maintaining normal bodily functions?

asked Feb 12 in Medicinal Chemistry by BNOHumberto0 (2.0k points)

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How does the coordination chemistry of metalloenzymes and metalloproteins contribute to their catalytic activity? Provide an example of a metalloenzyme or metalloprotein and explain the role of the metal ion in its catalytic mechanism.

asked Feb 12 in Coordination Chemistry by MarilouBinga (2.4k points)

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What are the potential medicinal properties and mechanisms of action of the natural product curcumin, and how can those properties be optimized through chemical modifications?

asked Feb 12 in Medicinal Chemistry by AntoinetteWo (2.0k points)

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What are the key factors that need to be considered when designing a polymer-based biomaterial for tissue engineering applications, and how do these factors affect the performance and biocompatibility of the material?

asked Feb 12 in Polymer Chemistry by OliveMatthae (2.1k points)

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How does the coordination chemistry of metalloenzymes and metalloproteins relate to their respective functions? Provide examples of metalloenzymes and metalloproteins and explain how their coordination chemistry affects their activity.

asked Feb 12 in Coordination Chemistry by AWSReginald (2.2k points)

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How can we design drugs to target specific neurotransmitters in the brain associated with Parkinson's disease, while minimizing off-target effects on other neurotransmitters?

asked Feb 12 in Medicinal Chemistry by RobynButz517 (1.9k points)

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How can we design novel antiviral agents that target viral enzymes with high specificity and potency, but have minimal off-target effects on host cell proteins?

asked Feb 12 in Medicinal Chemistry by AudraNowlin6 (2.2k points)

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How can we design drugs to specifically target mutated genes responsible for genetic disorders, while minimizing adverse effects on healthy cells and tissues?

asked Feb 12 in Medicinal Chemistry by StephaineCro (1.8k points)

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How does the density functional theory calculations of electronic properties of materials change when the applied external electric field increases or decreases? Provide key factors that can affect the accuracy of the electronic property predictions.

asked Feb 12 in Computational Chemistry by RamiroShockl (2.3k points)

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How does the electronic structure of a copper atom change when it forms a bond with an oxygen atom using Density Functional Theory calculations?

asked Feb 12 in Computational Chemistry by NilaBody107 (1.7k points)

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How can we design new drug molecules that selectively target the inflammatory pathways in the body without causing unwanted side effects?

asked Feb 12 in Medicinal Chemistry by Hugo83583981 (1.5k points)

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How can we design drugs that target specific types of cancer cells, such as lung cancer or breast cancer, while minimizing the damage to healthy cells?

asked Feb 12 in Medicinal Chemistry by IvyHogan8844 (1.6k points)

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How can we design an efficient system for the recovery of valuable metals such as gold, silver, and copper from electronic waste, while minimizing the amount of hazardous waste generated in the process?

asked Feb 12 in Chemical engineering by CarmaC633252 (1.7k points)

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How can we design an efficient industrial waste treatment system that minimizes the environmental impact of hazardous waste disposal and meets regulatory standards?

asked Feb 12 in Environmental Chemistry by BrigetteCors (2.5k points)

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How do different cooking methods affect the levels of pesticide residues in food?

asked Feb 12 in Environmental Chemistry by MariamPaine (1.9k points)

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How can we create a more hands-on approach in teaching chemistry for students who have limited opportunities for laboratory experimentation?

asked Feb 12 in Chemical education by SGDJenifer99 (2.0k points)

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How effective are current environmental regulations in mitigating hazardous waste pollution, and what advancements can be made in enforcing them to promote better environmental protection?

asked Feb 12 in Environmental Chemistry by LarhondaKeel (1.6k points)

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What type of bonding is present in diamond, and how can you distinguish it from other types of bonding in solids?

asked Feb 13 in Chemical bonding by CorneliusChi (1.6k points)

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How can we design drugs to treat metabolic disorders in a way that minimizes unwanted side effects and maximizes therapeutic efficacy?

asked Feb 12 in Medicinal Chemistry by PartheniaBar (2.2k points)

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What is the effect of coadministration of Warfarin and Aspirin on the pharmacokinetics and pharmacodynamics of each drug?

asked Feb 12 in Medicinal Chemistry by EmmettVerdin (2.2k points)

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