Question

Between meals, when the level of blood glucose drops below a certain point, a signal is sent to what organ saying “make more glucose"?

Answer 1

liver

Shortly after eating, there is a surplus of glucose in the body. Some of it will be used immediately, but the rest is stored in the form of glycogen. Between meals, when the level of glucose in the blood drops below a certain point, a signal is sent to the liver that says make more glucose.  In response, the glycogen in the liver is broken down and the resulting glucose is released into the bloodstream.