surface area
As a cell grows, its volume increases more quickly than its surface area. If a cell was to get very large, the small surface area would not allow enough nutrients to enter the cell quickly enough for the cells needs. This idea is explained in Figure below . However, large cells have a way of dealing with some size challenges. Big cells, such as some white blood cells, often grow more nuclei so that they can supply enough proteins and RNA for the cells requirements. Large, metabolically active cells often have lots of cell protrusions, resulting in many folds throughout the membrane. These folds increase the surface area available for transport of materials into or out of the cell. Such cell types are found lining your small intestine, where they absorb nutrients from your food through protrusions called microvilli .