tight junction
A tight junction is a watertight seal between two adjacent animal cells Figure 3.17b . Proteins hold the cells tightly against each other. This tight adhesion prevents materials from leaking between the cells. Tight junctions are typically found in the epithelial tissue that lines internal organs and cavities, and composes most of the skin. For example, the tight junctions of the epithelial cells lining the urinary bladder prevent urine from leaking into the extracellular space. Also found only in animal cells are desmosomes, which act like spot welds between adjacent epithelial cells Figure 3.17c . They keep cells together in a sheet-like formation in organs and tissues that stretch, like the skin, heart, and muscles. Gap junctions in animal cells are like plasmodesmata in plant cells in that they are channels between adjacent cells that allow for the transport of ions, nutrients, and other substances that enable cells to communicate Figure 3.17d . Structurally, however, gap junctions and plasmodesmata differ.