epithelium
A desmosome is a cell junction specialized for cell-to-cell adhesion. They are found in simple and stratified squamous epithelium, and in muscle tissue where they bind muscle cells to one another. These junctions are composed of complexes of cell surface adhesion proteins and linking proteins. These proteins have both an intracellular and extracellular region. Inside the cell, they attach to intracellular filaments of the cytoskeleton. Outside the cell, they attach to other adhesion proteins.