nucleotides
a When pyrimidine or purine and a sugar react to form a glycosidic bond, a nucleoside is produced. Adding a phosphoric acid group to the sugar of a nucleoside produces a nucleotide. b Nucleotides link together to form long polymeric chains. A DNA molecule consists of two such chains held together by hydrogen bonding between the purine and pyrimidine components on different chains. Mutations in the DNA of an organism may lead to the synthesis of defective proteins. Phenylketonuria PKU , for example, is a condition caused by a defective enzyme. Left.