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Where is most of the cell's dna contained?

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nucleus

Although most of a cell's DNA is contained in the cell nucleus, mitochondria have their own DNA. Mitochondria also have the machinery to manufacture their own RNAs and proteins. The human mitochondrial DNA sequence has 16,569 base pairs encoding 37 total genes: 22 tRNA genes, 2 rRNA genes, and 13 peptide genes. The 13 mitochondrial peptides in humans are integrated into the inner mitochondrial membrane, along with proteins encoded by nuclear genes.

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