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What is the main difference between eukaryotic and prokaryotic cells?

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eukaryotic cells have a nucleus

There are two basic types of cells, prokaryotic cells and eukaryotic cells . The main difference between eukaryotic and prokaryotic cells is that eukaryotic cells have a nucleus . The nucleus is where cells store their DNA , which is the genetic material. The nucleus is surrounded by a membrane. Prokaryotic cells do not have a nucleus. Instead, their DNA floats around inside the cell. Organisms with prokaryotic cells are called prokaryotes . All prokaryotes are single-celled  unicellular  organisms. Bacteria and Archaea are the only prokaryotes. Organisms with eukaryotic cells are called eukaryotes . Animals, plants, fungi, and protists are eukaryotes. All multicellular organisms are eukaryotes. Eukaryotes may also be single-celled.

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