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What human disease is caused by a defective enzyme that is unable to produce melanin, the pigment responsible for the color of skin and hair?

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albinism

untreated, it produces severe brain damage and mental retardation. Albinism is caused by a defective enzyme that is unable to produce melanin, the pigment responsible for the color of skin and hair. Cystic fibrosis, the most common inherited disease in the United States, blocks pancreatic function and causes thick mucus secretions that make breathing difficult. An area of intense research in combating cancer involves the synthesis of drugs that stop uncontrolled cell growth by interfering with DNA replication.

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