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What decreases with the loss of subsequent protons?

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acid strength

Polyprotic Acids and Bases As you learned in Chapter 4 "Reactions in Aqueous Solution", polyprotic acids such as H2SO4, H3PO4, and H2CO3 contain more than one ionizable proton, and the protons are lost in a stepwise manner. The fully protonated species is always the strongest acid because it is easier to remove a proton from a neutral molecule than from a negatively charged ion. Thus acid strength decreases with the loss of subsequent protons, and, correspondingly, the pKa increases. Consider H2SO4, for example: Figure 16.5.

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