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What is the difference between geometrical isomers and optical isomers in coordination compounds? Provide an example of each and explain its significance in coordination chemistry.
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Coordination Chemistry
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What is the difference between geometrical isomerism and optical isomerism in coordination compounds, and how do you identify them using spectroscopic methods?
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How do genetic variations affect the metabolism and efficacy of drugs commonly used to treat cardiovascular diseases?
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How do genetic variations impact the effectiveness and toxicity of drugs used in the treatment of hypertension? Provide specific examples of genetic variations and corresponding drugs.
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How do genetic variations affect the response of different individuals to the same drug and how can medicinal chemists use this information to design personalized treatments?
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How do genetic variations affect the metabolism and effectiveness of drugs used in the treatment of diabetes, and what are the implications of this for personalized medicine?
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How do genetic variations affect drug response in patients with specific diseases such as cardiovascular diseases or cancer?
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Medicinal Chemistry
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How does genetic variation influence the metabolism and efficacy of anti-cancer drugs in different patient populations?
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How does genetic variation influence drug response and efficacy in patients with cancer? Specifically, investigate the relationship between genetic markers and the response to chemotherapy drugs used in cancer treatment.
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Medicinal Chemistry
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What are the effects of genetic variation on drug response in the treatment of breast cancer, and how can medicinal chemists develop personalized therapies based on pharmacogenetic data?
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How does genetic variation affect the metabolism and effectiveness of clopidogrel, a commonly used antiplatelet drug, and what are the implications for personalized medicine?
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Medicinal Chemistry
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How does genetic variability affect the metabolization and efficacy of anti-cancer drugs in patients with different CYP2D6 genotypes?
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How does genetic variability influence drug response and efficacy in the treatment of cancer patients, specifically for the chemotherapy drug cisplatin?
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Medicinal Chemistry
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What are the advantages and limitations of using gel permeation chromatography for the characterization of a polymer sample?
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How can we determine the molecular weight distribution of a polymer using gel permeation chromatography (GPC)?
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Polymer Chemistry
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How can we use gel permeation chromatography (GPC) to determine the molecular weight distribution of a polymer sample?
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How can we quantitatively determine the molecular weight distribution of a polymer using gel permeation chromatography (GPC) and what are the important parameters to optimize for accurate results?
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What are the differences between gel permeation chromatography and size exclusion chromatography, and how can these techniques be used to characterize polymers with different molecular weights and distributions?
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Feb 13
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Polymer Chemistry
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What is the structure and bonding of the metal complexes in gadolinium-based metallofullerenes, and how do they affect the magnetic properties of the compound?
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Feb 13
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Coordination Chemistry
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How does the activation of G protein-coupled receptors (GPCRs) lead to the activation of downstream signal transduction pathways in biochemical terms?
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