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How do changes in the phosphorylation state of proteins within a cell’s signal transduction pathway affect the activation of downstream enzymes and ultimate cellular response? Provide examples of specific signal transduction pathways and how modulating these phosphorylation events can impact cellular behavior.

asked Jan 31 in BioChemistry by NannieRodger (430 points)

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How do changes in the number of layers or types of impurities affect the electronic and optical properties of graphene and other 2D materials?

asked Jan 31 in Quantum Chemistry by Eddie97G1445 (310 points)

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How do changes in the molecular structure of a conjugated polymer affect its electronic and optical properties, and how can we calculate these changes using quantum chemistry methods?

asked Jan 31 in Quantum Chemistry by DeclanRedmon (430 points)

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How do changes in the metabolite concentrations of specific pathways impact the overall cellular metabolism and how can this be studied using systems biology approaches?

asked Jan 31 in BioChemistry by SilasXqz4857 (370 points)

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How do changes in the lipid composition of a cell membrane affect its permeability to specific molecules? Provide examples of lipids that increase or decrease membrane permeability and explain why this occurs on a molecular level.

asked Jan 31 in BioChemistry by NevaTegg7848 (450 points)

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How do changes in the expression of lipid signaling enzymes affect the metabolism and signaling pathways within cells?

asked Jan 31 in BioChemistry by JerrodLeidig (250 points)

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1 answer 57 views

How do changes in the electronic structure of reactants affect the rate and mechanism of electron transfer processes during redox reactions?

asked Jan 31 in Quantum Chemistry by LouiePickett (330 points)

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How do changes in the electronic structure of an enzyme’s active site affect its catalytic activity in the reaction of interest? Use computational tools to investigate the specific changes that occur in the active site of an enzyme and determine the resulting effects on the reaction mechanism.

asked Jan 31 in Computational Chemistry by VHBMorgan997 (510 points)

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1 answer 83 views

How do changes in the electronic structure of a molecule affect its magnetic properties and how can these changes be quantitatively calculated using quantum chemistry calculations? Specifically, investigate how the presence or absence of unpaired electrons in a molecule influences its magnetic susceptibility and how this can be predicted using theoretical models.

asked Jan 31 in Quantum Chemistry by EmanuelBrier (350 points)

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How do changes in the electronic and magnetic properties of molecular magnets affect their stability and potential for use in magnetic data storage applications?

asked Jan 31 in Quantum Chemistry by Renee904111 (610 points)

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1 answer 53 views

How do changes in the DNA sequence affect the binding affinity and specificity of transcription factors to DNA?

asked Jan 31 in BioChemistry by BeatrizWerne (170 points)

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1 answer 65 views

How do changes in the DNA sequence affect the binding affinity and specificity of a transcription factor?

asked Jan 31 in BioChemistry by Jerrold99K8 (150 points)

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1 answer 60 views

How do changes in the concentrations of different hormones, such as insulin and glucagon, affect the regulation of blood glucose levels in the body? Provide a detailed explanation of the different signaling pathways involved in this process, including the roles of enzymes, cellular receptors, and second messengers. Furthermore, consider the impact of various physiological conditions, such as exercise or fasting, on hormone production and signaling. Finally, discuss the potential applications of this knowledge in the treatment of metabolic disorders, such as diabetes.

asked Jan 31 in BioChemistry by AnjaNoguera (490 points)

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How do changes in concentrations of enzymes and substrates affect the rate of a metabolic pathway? Provide a detailed explanation using the glycolysis pathway as an example.

asked Jan 31 in BioChemistry by JettMackinol (510 points)

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1 answer 81 views

How do changes in the composition of perovskite materials affect their electronic and optical properties, and what are the most effective methods for calculating and predicting these properties?

asked Jan 31 in Quantum Chemistry by HattieSteven (490 points)

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1 answer 52 views

How do changes in the atomic configuration affect the electronic and optical properties of perovskite materials, and how can we use quantum calculations to accurately predict these changes?

asked Jan 31 in Quantum Chemistry by Kristie70H50 (390 points)

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1 answer 56 views

How do changes in temperature affect the structure and dynamics of a lipid bilayer membrane? Use molecular dynamics simulations to investigate the changes in lipid bilayer properties as temperature increases or decreases.

asked Jan 31 in Computational Chemistry by RobbinTerril (430 points)

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1 answer 50 views

How do changes in temperature affect the rate of enzyme-catalyzed reactions?

asked Jan 31 in BioChemistry by IngeDeBernal (390 points)

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1 answer 59 views

How do changes in temperature affect the permeability of cell membranes?

asked Jan 31 in BioChemistry by MariHeney752 (310 points)

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How do changes in temperature affect the folding and stability of a specific protein structure? Use molecular dynamics simulations to analyze the role of temperature in the folding pathway and identify key structural changes that occur under different temperature conditions.

asked Jan 31 in Computational Chemistry by SusannaCaste (210 points)

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