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How can we design drugs that target specific genetic mutations implicated in diseases such as cystic fibrosis, sickle cell anemia, and Huntington's disease?

asked Feb 12 in Medicinal Chemistry by Hugo83583981 (1.5k points)

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What are the design principles and challenges in developing drugs that target specific genetic mutations implicated in diseases like cystic fibrosis and Huntington's disease? How can these drugs be optimized for maximum efficacy and minimal side-effects?

asked Feb 12 in Medicinal Chemistry by DaisyThwaite (1.9k points)

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How can we design drugs that target specific genetic mutations causing genetic disorders such as cystic fibrosis or sickle cell anemia, while avoiding negative side effects on healthy cells and organs?

asked Feb 12 in Medicinal Chemistry by TVMBeulah703 (2.4k points)

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How can we design drugs that target specific genes responsible for causing genetic disorders, such as sickle cell anemia or cystic fibrosis, while avoiding damage to healthy genes?

asked Feb 12 in Medicinal Chemistry by MikelHead373 (2.3k points)

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How can we design drugs that target the dopamine receptors in the brain to effectively treat Parkinson's disease while also minimizing unwanted side effects such as dyskinesia?

asked Feb 12 in Medicinal Chemistry by SamaraBradle (1.5k points)

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How can we design drugs that specifically target the spike protein of the SARS-CoV-2 virus while avoiding interference with other cellular proteins?

asked Feb 12 in Medicinal Chemistry by Sung68J56969 (2.2k points)

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How can we design drugs that specifically target the protein structure of the SARS-CoV-2 virus to inhibit its replication and prevent the spread of COVID-19?

asked Feb 12 in Medicinal Chemistry by PhillipPugli (2.1k points)

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1 answer 36 views

How can we design drugs that specifically target the HIV virus and prevent its replication in the human body?

asked Feb 12 in Medicinal Chemistry by OmerFinsch09 (2.1k points)

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1 answer 37 views

How can we design drugs that specifically target the angiotensin converting enzyme (ACE) for the treatment of hypertension?

asked Feb 12 in Medicinal Chemistry by OlgaMoonligh (2.2k points)

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1 answer 26 views

How can we design drugs that specifically target Gram-negative bacteria without harming the beneficial bacteria in the human microbiome?

asked Feb 12 in Medicinal Chemistry by OlgaMoonligh (2.2k points)

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How can we design drugs that specifically target gram-negative bacteria without harming the surrounding healthy cells and microbiota?

asked Feb 12 in Medicinal Chemistry by MarkusOrdone (1.9k points)

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1 answer 40 views

How can we design drugs that specifically target cancer cells without damaging healthy cells?

asked Feb 12 in Medicinal Chemistry by EdwardoO6191 (2.5k points)

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1 answer 33 views

How can we design drugs that specifically target cancer cells with HER2 receptors?

asked Feb 12 in Medicinal Chemistry by ShaunBehan45 (2.8k points)

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1 answer 28 views

How can we design drugs that specifically target bacteria without harming human cells, and what chemical modifications would be necessary to achieve this specificity?

asked Feb 12 in Medicinal Chemistry by KaiRazo33412 (1.9k points)

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1 answer 21 views

How can we design drugs that specifically target and treat the symptoms of Parkinson's disease, without causing harmful side effects to healthy neurons in the brain?

asked Feb 12 in Medicinal Chemistry by MariRosetta0 (2.2k points)

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How can we design drugs that specifically target and kill cancer cells while leaving healthy cells intact?

asked Feb 12 in Medicinal Chemistry by Benjamin55Q0 (2.1k points)

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1 answer 37 views

How can we design drugs that specifically target and inhibit the growth of gram-negative bacteria, such as E. coli or P. aeruginosa, while leaving the beneficial gut microbiota unharmed?

asked Feb 12 in Medicinal Chemistry by JonelleCouls (1.8k points)

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1 answer 22 views

How can we design drugs that specifically target and bind to the active site of the enzyme responsible for a particular disease, while avoiding off-target effects on other enzymes or receptors in the body?

asked Feb 12 in Medicinal Chemistry by Bernice06378 (1.4k points)

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1 answer 11 views

How can we design drugs that selectively target the entry proteins of the SARS-CoV-2 virus while not affecting the normal function of similar entry proteins in human cells, within the constraints of medicinal chemistry principles?

asked Feb 12 in Medicinal Chemistry by CamillePiazz (1.8k points)

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1 answer 35 views

How can we design drugs that selectively target specific receptors in the central nervous system to treat neurological disorders such as Parkinson's Disease or Alzheimer's Disease?

asked Feb 12 in Medicinal Chemistry by KreogMoore5 (6.4k points)

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