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How does alternative splicing of pre-mRNA molecules produce different protein isoforms and how can this mechanism be utilized in drug target identification and therapy development?

asked Jan 31 in BioChemistry by JannaWales93 (2.0k points)

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1 answer 83 views

How does alternative splicing of pre-mRNA affect the function of proteins produced in eukaryotic cells?

asked Jan 31 in BioChemistry by BFFRachelle (1.8k points)

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How does alternative splicing of pre-mRNA molecules affect the final functional forms of RNA and protein products in the context of RNA processing?

asked Jan 31 in BioChemistry by SarahWeston5 (2.0k points)

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1 answer 84 views

How does alternative splicing impact the formation of different isoforms of specific proteins, and how do these isoforms affect biological function?

asked Jan 31 in BioChemistry by AlexK0785479 (1.8k points)

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1 answer 103 views

How does alternative splicing affect the structure and function of RNA transcripts in eukaryotic cells? Provide examples of proteins that result from alternative splicing and explain how their functions differ from the unspliced form.

asked Jan 31 in BioChemistry by FranciscoHen (1.7k points)

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1 answer 86 views

How does alternative splicing of pre-mRNA lead to the formation of multiple protein isoforms and what role does it play in cellular processes?

asked Jan 31 in BioChemistry by MindyR870320 (1.6k points)

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1 answer 86 views

How does alternative splicing impact the final structure and function of RNA molecules, and how can this knowledge be applied in drug development for diseases caused by RNA splicing errors?

asked Jan 31 in BioChemistry by RandellBeggs (2.0k points)

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1 answer 87 views

How does alternative splicing affect the function of RNA in gene expression? Provide specific examples of alternative splicing patterns and their resulting changes in protein isoforms.

asked Jan 31 in BioChemistry by MarcellaFurp (1.7k points)

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1 answer 88 views

How does the mechanism of Alternative Splicing work in RNA processing? Provide a detailed explanation of the different mechanisms that regulate the splicing process, and discuss the factors that contribute to the selection of specific splicing patterns. Additionally, compare and contrast the advantages and disadvantages of Alternative Splicing in terms of their impact on gene expression and cellular function.

asked Jan 31 in BioChemistry by Samira94683 (2.2k points)

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1 answer 104 views

How does alternative RNA splicing affect the structure and function of proteins, and what are the potential implications for human health and disease?

asked Jan 31 in BioChemistry by UteKqe974841 (1.9k points)

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1 answer 84 views

How does altering the pressure affect the equilibrium position in a reversible chemical reaction, and what are the factors that determine whether the reaction will shift to the side with a greater number of moles of gas or to the side with a lesser number of moles of gas? Provide an explanation using an example of a gaseous reaction.

asked Jan 31 in Chemical equilibrium by NilaBody107 (1.7k points)

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1 answer 102 views

How does altering the pH level affect the equilibrium position of a redox reaction, and what is the relationship between the dissociation constant and pH in such a reaction? Provide an example to explain the concept.

asked Jan 31 in Chemical equilibrium by CedricNicker (1.9k points)

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1 answer 115 views

How does altering the concentrations of reactants and products at equilibrium affect the rate of the forward and reverse reactions in a chemical system?

asked Jan 31 in Chemical kinetics by DanielleVanw (2.3k points)

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1 answer 98 views

What is the effect of altering the concentration of reactants and products on the equilibrium constant and reaction rate of a reversible reaction?

asked Jan 31 in Chemical kinetics by LynwoodLundg (1.5k points)

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1 answer 126 views

How does altering the chemical structure of a small molecule affect its binding affinity to a specific protein involved in a protein-protein interaction, as predicted by molecular docking studies?

asked Jan 31 in Computational Chemistry by QJXClarice2 (2.5k points)

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1 answer 32 views

How would altering the chemical structure of a drug impact its pharmacokinetics in the body and what factors need to be considered to optimize drug efficacy?

asked Jan 31 in Medicinal Chemistry by RandellBeggs (2.0k points)

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1 answer 105 views

How does altering the chemical structures of a drug affect its pharmacodynamics and target interaction in the human body?

asked Jan 31 in Medicinal Chemistry by PercyEdmonds (1.8k points)

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1 answer 82 views

How does the alteration in lipid metabolism cause metabolic disorders such as diabetes and obesity? Examine the role of lipid signaling and metabolism in regulating the production and metabolism of lipids and their impact on cellular function and disease development.

asked Jan 31 in BioChemistry by EloisaLeavit (1.5k points)

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1 answer 27 views

How do alterations in the lipid metabolism and signaling pathways affect the development of neurological disorders such as Alzheimer's disease?

asked Jan 31 in BioChemistry by KristiMoore (2.0k points)

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1 answer 84 views

How does the allosteric regulation of the enzyme phosphofructokinase play a key role in the regulation of glucose metabolism during glycolysis?

asked Jan 31 in BioChemistry by ErikGendron8 (1.4k points)

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