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How can we use structure-based drug design to develop a new antibiotic that specifically targets the cell wall of Gram-negative bacteria, without affecting the healthy cells of the host organism?
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How can we use structure-based drug design approaches to develop more effective chemotherapeutic agents for the treatment of breast cancer?
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How can we use structure-based drug design to create new antiviral compounds that target the specific proteins or enzymes involved in viral replication?
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How can we use structure-based drug design to develop more effective treatments for autoimmune diseases such as rheumatoid arthritis?
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How can the use of structure-based drug design help in the development of new treatments for respiratory diseases such as asthma and COPD?
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What is the difference between structural isomerism and stereoisomerism in organic compounds, and how can you distinguish between them? Provide examples to illustrate your answer.
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What is the effect of strain on the electronic and optical properties of graphene? What are the changes in the energy band structure and excitonic properties of strained graphene compared to the unstrained graphene?
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How can we relate the concept of stoichiometry to real-world scenarios, such as cooking or manufacturing industries? Provide at least three examples and explain how stoichiometry is used in these scenarios.
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Chemical education
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How do steroid hormones such as cortisol and testosterone interact with their target cell receptors, and what are the chemical mechanisms underlying their signaling pathways?
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What is the chemical mechanism of step-growth polymerization, and how does it differ from chain-growth polymerization in terms of molecular weight distribution and reaction rate?
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What is the difference between step-growth and chain-growth polymerization reactions and how do their mechanisms affect the properties of the resulting polymer?
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How can you effectively prepare for chemistry exams to overcome the inadequate preparation? Provide a step-by-step study plan that includes various strategies such as active reading, practice problems, and seeking help from a tutor or teacher.
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Chemical education
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What are the photochemical properties of spiropyran and how do these properties relate to its photochromic behavior?
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How do the spectroscopic techniques like UV-Vis, IR, and NMR help in characterizing coordination compounds and determining their electronic and geometric structure?
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Coordination Chemistry
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How do the specific binding interactions between carbohydrates and proteins differ from non-specific interactions? Provide specific examples of each and explain the implications of these differences in biological systems.
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How do specific amino acid sequences in transcription factors contribute to DNA-protein interactions and regulation of gene expression?
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How do specific amino acid residues in a DNA-binding protein contribute to its binding affinity and specificity for a particular sequence of DNA?
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BioChemistry
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How do specific amino acid residues contribute to the formation and stability of protein-protein complexes?
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BioChemistry
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How do specific amino acid residues affect the stability of DNA-protein complexes? Provide experimental evidence using in vitro assays.
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How do specific air pollutants, such as particulate matter and ozone, impact human health on a molecular and cellular level? And how can advancements in environmental chemistry be used to mitigate these negative effects?
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Feb 14
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Environmental Chemistry
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