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Design a drug that could potentially treat Type 2 Diabetes by targeting an enzyme or transport protein involved in glucose metabolism. Consider the pharmacokinetics and pharmacodynamics of the drug and include a detailed mechanism of action.

asked 3 days ago in Medicinal Chemistry by Emerson1291 (590 points)

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1 answer 39 views

Design a drug that can selectively target and inhibit the activity of the enzyme responsible for converting saturated fatty acids to mono-unsaturated fatty acids in the liver, without affecting the activity of other important enzymes involved in lipid metabolism pathways. How would you potentially test the efficacy of this drug in vivo?

asked 3 days ago in BioChemistry by IsisHampton (590 points)

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1 answer 42 views

Design a distillation column to separate a mixture that contains 40% ethanol and 60% water by weight with a desired ethanol purity of 95%. The feed rate of the mixture is 100 kg/hr and the reflux ratio is 3:1. Determine the number of theoretical plates required and the height of the column. Assume that the total condenser and reboiler are both at 100°C and that the distillate leaving the column is 90% liquid and 10% vapor.

asked 3 days ago in Chemical engineering by MadgeGreene4 (370 points)

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1 answer 45 views

Design a distillation column to separate a mixture of ethanol and water. The feed stream contains 20 mol% ethanol and the desired distillate should contain at least 95 mol% ethanol. The reflux ratio should be 3:1 and the column should have 25 theoretical trays. Determine the composition of the distillate, bottoms, and the optimal feed tray location to achieve the desired separation. Use McCabe-Thiele method to determine the number of theoretical trays required.

asked 3 days ago in Chemical engineering by TinaStamps81 (330 points)

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1 answer 43 views

Design a distillation column to separate a mixture of ethanol and water with an initial composition of 40% ethanol and 60% water. The column should achieve a separation of at least 95% ethanol in the distillate product. The available packing materials are Pall rings with a diameter of 1.5 inches and a height of 2 inches. The column inlet flow rate is 1000 kg/hr with a pressure of 1 atm and a temperature of 80°C. The column should have 25 theoretical plates and operate at reflux ratios ranging from 1.5 to 3.0. Additionally, the column diameter should not exceed 3 feet. Provide the design calculations and specifications for the distillation column.

asked 3 days ago in Chemical engineering by JacquelynP76 (650 points)

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1 answer 43 views

Design a distillation column to separate a mixture of ethanol and water when the initial mixture contains 30% ethanol and 70% water. The desired final concentration of ethanol in the distilled product is 95%. The distillation column is 14 trays high and the reflux ratio is set at 2.2. Calculate the minimum number of theoretical trays required in the distillation column and provide the final composition of the ehtanol product stream.

asked 3 days ago in Chemical engineering by KarinGallego (630 points)

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1 answer 40 views

Design a distillation column to separate a mixture of ethanol and water using McCabe-Thiele Method. The feed contains 50 mol% ethanol and the distillate should have a purity of at least 95 mol% ethanol. The reflux ratio is 2.5 and the boil-up ratio is 1.5. The column must have 10 theoretical plates. Determine the number of trays above the feed and below the feed and the corresponding compositions of the distillate and bottoms.

asked 3 days ago in Chemical engineering by ClydeNorwood (350 points)

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1 answer 32 views

Design a distillation column to separate a mixture of cyclohexane and toluene with a feed composition of 60 mol% cyclohexane and 40 mol% toluene. The distillate product should contain a minimum of 90 mol% cyclohexane and the bottom product should contain a maximum of 10 mol% cyclohexane. You have access to a temperature range of 80-150°C and a pressure range of 1-5 atm. Determine the number of theoretical plates required for this separation and the corresponding reflux ratio.

asked 3 days ago in Chemical engineering by GladysHailes (510 points)

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1 answer 38 views

Design a distillation column to separate a mixture of acetone and water containing 35% (by mole) acetone with a feed rate of 1000 kg/hr. The desired purity of the overhead product is 99% acetone, and the bottom product should contain no more than 0.5% acetone. The available reflux ratio is 2.5, and the feed is at its boiling point at normal atmospheric pressure. Determine the number of theoretical trays required, the optimum feed tray location, and the reflux and boilup rates needed for the design.

asked 3 days ago in Chemical engineering by Terra8271834 (390 points)

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1 answer 33 views

Design a distillation column that separates a mixture of ethanol and water with a 95% ethanol purity and a production rate of 1000 liters per hour. The mixture contains 50% ethanol and 50% water by volume. The distillation column should operate at a pressure of 1 atm and a temperature range of 78-85°C. Assume that the feed enters the column as a saturated liquid and that the overhead product is 90% ethanol, while the bottom product is 5% ethanol. Determine the number of stages required and the reflux ratio for this system.

asked 4 days ago in Chemical engineering by Douglas62730 (610 points)

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1 answer 34 views

Design a distillation column that separates a mixture of benzene and toluene with a feed of 50 mol% benzene and 50 mol% toluene, into two product streams: one with a purity of 99% benzene and the other with a purity of 99% toluene. The total distillate flow rate should be 80% of the feed flow rate and the reflux ratio should be 1.5 times the minimum reflux ratio. Provide a complete design including the required stages, the reboiler duty, and the reflux flow rate.

asked 4 days ago in Chemical engineering by CallumBoynto (370 points)

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1 answer 28 views

Design a distillation column that can separate a mixture consisting of 40% acetone, 30% methanol, and 30% ethanol with a feed rate of 100 mol/h. The distillate should consist of at least 98% acetone, and the bottom product should contain no more than 1% acetone. You may assume that the column operates at a constant pressure and has 20 equilibrium stages. Determine the reflux ratio and the number of trays required to achieve this separation.

asked 4 days ago in Chemical engineering by LeonardoHyla (710 points)

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1 answer 44 views

Design a distillation column that can effectively separate a mixture of ethanol and water with a composition of 60% ethanol and 40% water. The distillation column should have a reflux ratio of 1.5 and a total of 10 theoretical stages. Determine the operating conditions (temperature, pressure, and feed rate) needed to achieve a distillate product with a composition of 95% ethanol and a bottoms product with a composition of 5% ethanol.

asked 4 days ago in Chemical engineering by MoseTall8858 (530 points)

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1 answer 36 views

Design a distillation column that can effectively separate a mixture of 75% ethanol and 25% water with a feed rate of 1000 kg/hr. Your column should produce a distillate with a composition of at least 95% ethanol and a bottom product with no more than 5% ethanol. Assume the feed mixture enters the column at its boiling point and you have access to a cooling water supply at 20°C for the condenser. Provide a detailed design and justification of your column's operating conditions including temperatures, pressures, and flow rates.

asked 4 days ago in Chemical engineering by MadelineRobe (770 points)

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1 answer 47 views

Design a distillation column that can effectively separate a mixture containing 50 wt% methanol and 50 wt% water. The column should produce a distillate with no more than 5 wt% methanol and a bottom product with no more than 2 wt% water. The feed rate is 1000 kg/h and the column must operate at atmospheric pressure. Assume that the feed is a saturated liquid and that the methanol-water mixture behaves as an ideal solution. Provide the design specifications for the column, including the number of trays or packing height, diameter, and other necessary specifications.

asked 4 days ago in Chemical engineering by ShawneeSalmo (290 points)

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1 answer 41 views

Design a distillation column for the separation of a mixture containing 35% Ethanol and 65% Water. Calculate the number of theoretical plates required for the separation if the column operates at a pressure of 1 atm and a reflux ratio of 1.5.

asked 4 days ago in Chemical engineering by AletheaFiori (390 points)

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1 answer 25 views

Design a distillation column for the separation of a mixture composed of 50% ethanol and 50% water. The column must produce a distillate that is at least 95% ethanol and a bottoms stream that is at most 5% ethanol. The feed rate is 1000 kg/h and the reflux ratio is to be determined by the student. Provide the complete design of the distillation column including the number of theoretical trays, feed tray location, and the diameter of the column.

asked 4 days ago in Chemical engineering by EliseHibbs7 (430 points)

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1 answer 29 views

Design a distillation column for the separation of a binary mixture of ethanol and water, with a feed consisting of 50 weight percent ethanol and 50 weight percent water. The column should be able to produce a distillate product containing at least 90 weight percent ethanol, with a recovery of at least 95 weight percent of the ethanol in the feed. The feed rate is 1000 kg/hr and the reflux ratio should be optimized for the best separation efficiency. Determine the number of theoretical trays required for the column design and calculate the heat load required for the operation of the column.

asked 4 days ago in Chemical engineering by LPFVirgie959 (590 points)

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1 answer 50 views

Design a distillation column for the separation of a binary mixture consisting of ethanol and water. The feed mixture contains 40 mol% ethanol and 60 mol% water, and the desired product purity is 95 mol% ethanol. The feed rate is 1000 kg/hr and the column should operate at atmospheric pressure. Calculate the number of theoretical plates required to achieve the desired separation and determine the corresponding height and diameter of the column.

asked 4 days ago in Chemical engineering by EstebanKenne (470 points)

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1 answer 26 views

Design a counter-current heat exchanger to cool 10,000 liters per hour of cyclohexane at 110°C down to 50°C, while heating 7,500 liters per hour of water at 25°C up to 80°C. The cyclohexane will be cooled by water which enters the heat exchanger at 90°C and exits at 60°C. The overall heat transfer coefficient is expected to be 1,000 W/m2K. Determine the required heat transfer area and the pressure drop across the heat exchanger.

asked 4 days ago in Chemical engineering by IleneNobles (190 points)

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