Recent questions in Chemistry

0 votes

1 answer 42 views

How does the binding of a specific protein to DNA affect its structure and dynamics, and how can we use molecular dynamics simulations to explore the underlying molecular mechanisms of this interaction?

asked Feb 17 in Computational Chemistry by GracieGainfo (2.2k points)

0 votes

1 answer 40 views

How does the binding of a small molecule inhibitor affect the conformational dynamics of a protein target, as revealed by molecular dynamics simulations?

asked Feb 17 in Computational Chemistry by SergioCrews1 (1.9k points)

0 votes

1 answer 43 views

How does the binding of a metal ion to the active site of an enzyme affect its catalytic activity? Provide an example of a metalloenzyme and discuss the role of the metal ion in its enzymatic activity.

asked Feb 17 in Coordination Chemistry by RogerDenning (2.4k points)

0 votes

1 answer 57 views

How does the binding of a ligand to a receptor trigger a signal transduction pathway in biochemistry?

asked Feb 17 in BioChemistry by FinleySalern (1.6k points)

0 votes

1 answer 37 views

How does the binding of a ligand affect the conformation of a protein complex involved in DNA replication?

asked Feb 17 in BioChemistry by BelenPickard (2.3k points)

0 votes

1 answer 40 views

How does the binding of a ligand affect the stability of a protein complex?

asked Feb 17 in BioChemistry by AshleighFleg (2.1k points)

0 votes

1 answer 39 views

How does the binding of a hormone to a receptor result in the activation of intracellular signaling pathways?

asked Feb 17 in BioChemistry by SarahWeston5 (2.0k points)

0 votes

1 answer 36 views

How does the binding energy of a transition metal complex change as the metal's oxidation state increases, as determined by ab initio calculations?

asked Feb 17 in Computational Chemistry by CDEMargherit (1.7k points)

0 votes

1 answer 34 views

What are the key factors that govern the binding and activation of oxygen to the heme iron of myoglobin and hemoglobin? Discuss the coordination chemistry of these metalloproteins with respect to their biological function.

asked Feb 17 in Coordination Chemistry by CoreyBeck54 (2.2k points)

0 votes

1 answer 39 views

How does the binding affinity of protein-protein interactions change when using various ligands in molecular docking studies, and can these differences be used to design more effective drugs to treat specific diseases?

asked Feb 17 in Computational Chemistry by CorineSasaki (1.8k points)

0 votes

1 answer 35 views

How does the binding affinity of protein-protein interactions change with variations in temperature and pH?

asked Feb 17 in BioChemistry by GracieGainfo (2.2k points)

0 votes

1 answer 32 views

How does the binding affinity of an inhibitor molecule with a protein target change when the temperature and pH of the system are varied, as determined by a molecular dynamics simulation?

asked Feb 17 in Computational Chemistry by Marilynn3793 (2.1k points)

0 votes

1 answer 31 views

How does the binding affinity of a specific protein to DNA change in the presence of an external factor, such as a small drug molecule or a change in pH, as determined by molecular dynamics simulations?

asked Feb 17 in Computational Chemistry by RichelleVerr (2.1k points)

0 votes

1 answer 36 views

How does the binding affinity of a protein-protein interaction change with varying concentrations of each protein?

asked Feb 17 in BioChemistry by TonyaCombs22 (1.8k points)

0 votes

1 answer 38 views

How does the binding affinity of a protein-protein complex change with varying pH levels in the surrounding environment?

asked Feb 17 in BioChemistry by MaximoVardon (1.9k points)

0 votes

1 answer 43 views

How does the binding affinity of a protein-ligand complex change with varying pH values using molecular dynamics simulations?

asked Feb 17 in Computational Chemistry by Dannie89E20 (2.0k points)

0 votes

1 answer 37 views

How is the binding affinity of a particular protein-protein interaction affected by changes in pH?

asked Feb 17 in BioChemistry by Lizzie32E683 (1.8k points)

0 votes

1 answer 42 views

How does the binding affinity of a drug to its target receptor affect its pharmacological effects in the body?

asked Feb 17 in Medicinal Chemistry by MacDeLoitte (1.8k points)

0 votes

1 answer 38 views

How does the binding affinity between two specific protein molecules change under varying pH conditions? Provide a detailed explanation with experimental evidence and propose possible explanations for the observed changes.

asked Feb 17 in BioChemistry by TeshaDeuchar (1.9k points)

0 votes

1 answer 45 views

How does the binding affinity between two proteins affect the success rate of protein-protein interaction inhibitors designed using molecular docking studies?

asked Feb 17 in Computational Chemistry by CalvinHornin (1.6k points)

Categories