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How can we design small-molecule drugs to target the root cause of genetic disorders by correcting or restoring the function of mutated proteins, while avoiding off-target effects that can lead to toxicity or other side effects?

asked Feb 12 in Medicinal Chemistry by NicholeBueno (1.8k points)

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1 answer 127 views

How do different greenhouse gases (carbon dioxide, methane, nitrous oxide, etc.) contribute to global warming and what is the relative importance of each gas?

asked Feb 13 in Environmental Chemistry by Hulda4183859 (2.2k points)

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How does eutrophication affect the dissolved oxygen levels in aquatic ecosystems and what are the potential consequences for the ecosystem and its inhabitants?

asked Feb 13 in Environmental Chemistry by NanVanwagene (1.8k points)

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How does the oxidation state of a compound change during a reduction reaction? Provide an example of a reaction where this occurs in organic chemistry.

asked Feb 13 in Organic Chemistry by GreggTimperl (2.4k points)

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What is the role of glutamine synthetase in nitrogen assimilation and how does it function?

asked Feb 13 in BioChemistry by KWFErin73234 (1.9k points)

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How does the drug doxorubicin work in treating cancer, and what specific cellular processes and pathways does it target?

asked Feb 12 in Medicinal Chemistry by MargueriteSa (2.1k points)

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How do the intermolecular forces of different substances affect their boiling points, and how can we accurately predict the boiling point of a given substance based on its intermolecular forces?

asked Feb 13 in Chemical bonding by FranY1408156 (2.2k points)

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1 answer 141 views

How can we design and optimize the self-assembly of surfactant molecules to form ordered monolayers on solid surfaces with tunable properties, such as wettability, adhesion, and friction, for potential applications in nanotechnology and biomaterials?

asked Feb 12 in Physical Chemistry by VeolaBrifman (1.9k points)

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1 answer 132 views

How can we enhance the sensitivity and selectivity of a polymer-based sensor for detecting a specific analyte?

asked Feb 13 in Polymer Chemistry by CorrinePerre (2.1k points)

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1 answer 219 views

How can the surface functionalization of noble metal nanoparticles be optimized to enhance their catalytic activity for a specific reaction, such as the reduction of carbon dioxide to produce fuels?

asked Feb 11 in Materials Chemistry by LeeAlder0448 (1.5k points)

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What is the role of metal ions in the mechanism of metalloenzymes? Please provide specific examples of metalloenzymes and their corresponding metal ion cofactors.

asked Feb 13 in Coordination Chemistry by TiaraFitzgib (2.1k points)

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1 answer 135 views

What is the role of DNA polymerase III in the replication of DNA, and how does it proofread and repair errors in the newly synthesized strand?

asked Feb 12 in BioChemistry by EtsukoCantwe (1.8k points)

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1 answer 153 views

How do the chemical properties and composition of crude oil affect its behavior and impact on the environment during an oil spill?

asked Feb 12 in Environmental Chemistry by YaniraRhh59 (1.9k points)

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What is the chemical mechanism behind CFCs that lead to the destruction of ozone molecules?

asked Feb 12 in Environmental Chemistry by Marilynn3793 (2.1k points)

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What is the role of molecular chaperones in protein folding, and how do they assist in the folding process? What are the consequences of misfolded proteins, and how can these consequences be treated or prevented?

asked Feb 13 in BioChemistry by JanieCorso7 (1.9k points)

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How can we design drugs that target specific genetic mutations responsible for causing inherited diseases, such as cystic fibrosis or sickle cell anemia, while avoiding off-target effects on healthy cells?

asked Feb 12 in Medicinal Chemistry by ValeriaStrom (1.7k points)

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1 answer 121 views

What is the effect of varying temperature on the degree of polymerization in a Monte Carlo simulation of a polymer system consisting of ethylene monomers?

asked Feb 13 in Computational Chemistry by TawnyaI60415 (1.4k points)

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1 answer 125 views

How do hormones regulate glucose levels in the blood?

asked Feb 13 in BioChemistry by IWHJaxon1452 (2.1k points)

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1 answer 90 views

How does the metabolic pathway of nitrogen assimilation differ in plants and bacteria? Compare the process and the enzymes involved in both organisms.

asked Feb 14 in BioChemistry by MargieJobson (2.2k points)

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Identify the functional groups present in the molecule ethylene oxide (also known as oxirane) and explain its reactivity towards nucleophiles.

asked Feb 13 in Organic Chemistry by WilfredoWren (2.1k points)

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